New: the free Stackhaus Compass research dashboard, upload your labs
Healing & RecoveryAdvancedGray Area

SS-31

Elamipretide / Szeto-Schiller peptide

Low Dose
0.05 mg/kg/day
Medium Dose
0.25 mg/kg/day
Route
SubQ daily
Cycle Length
4–12 weeks

Mechanism of Action

Mitochondria-targeted antioxidant peptide. Concentrates in the inner mitochondrial membrane, reduces reactive oxygen species, and protects cardiolipin from oxidative damage.

Key Benefits

  • Mitochondrial protection and function improvement
  • Cardiac protection and recovery
  • Renal protection in ischemia-reperfusion
  • Reduced oxidative stress

Dosing Protocol

Low / Starting Dose
0.05 mg/kg/day
Medium / Maintenance Dose
0.25 mg/kg/day
Administration Route
SubQ daily
Half-Life
~hours
Frequency
Once daily
Cycle Length
4–12 weeks
Protocol Notes

Mitochondria-targeted antioxidant with promising cardiac and renal protection data.

Ideal Candidates

Heart failure, renal disease, mitochondrial dysfunction, aging.

Side Effects & Safety

Injection site reactions. Generally well-tolerated in trials.

Regulatory Status

Gray Area

Not on the 503A bulks list. Significant clinical trial data for cardiac indications.

Frequently asked

What is SS-31?+

SS-31 (Elamipretide / Szeto-Schiller peptide) is a peptide studied for mitochondrial protection and cardiac recovery. Mitochondria-targeted antioxidant peptide. Concentrates in the inner mitochondrial membrane, reduces reactive oxygen species, and protects cardiolipin from oxidative damage.

What is the dosing protocol for SS-31?+

Literature commonly references 0.05 mg/kg/day (low) to 0.25 mg/kg/day (maintenance) via SubQ daily, on a 4–12 weeks cycle. Educational reference only — a licensed Stackhaus Health provider sets any personalized protocol.

What is the regulatory status of SS-31?+

Not on the 503A bulks list. Significant clinical trial data for cardiac indications.

Where can I access SS-31?+

Research-grade SS-31 is available through Stackhaus Research. For a personalized, provider-reviewed protocol, consult a licensed clinician through Stackhaus Health.

More in Healing & Recovery

Educational Only. This information is not medical advice. Consult a qualified healthcare professional before starting any peptide protocol. Individual results vary. Personalized protocols and clinical care are provided through licensed providers via Stackhaus Health.